Ultrastructural alterations in adult Schistosoma mansoni , harbored in non-antihelminthic treated and low-inflammatory mice by transmission electron microscopy (TEM)
[39] [40] Pharmacology [edit] Pharmacokinetics [edit] A 2007 human pharmacokinetic study of sodium RLA demonstrated the maximum concentration in plasma and bioavailability are significantly greater than the free acid form, and rivals plasma levels achieved by intravenous administration of the free acid form
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they further derived a seven-gene signature (RAD51, CASP14, NEK10, PCP2, IDO1, CLSTN2, IGHG1) that stratified patients by risk and correlated with immune features and predicted drug sensitivities, suggesting lactylation signatures may inform prognosis and treatment selection [287]
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