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Such a non-protein cofactor is known as a "prosthetic group." R -lipoic acid functions as a prosthetic group for the biological activity of the following multienzyme complexes: The glycine cleavage system that catalyzes the decarboxylation of glycine coupled with the addition of a methylene group (-CH 2 ) to tetrahydrofolate to form 5,10-methylene tetrahydrofolate, an important cofactor in the synthesis of nucleic acids ( Figure 3 )

For instance, Tin et al

Here are a few available options: Oral supplementation with bioavailable liposomal, reduced, or S-acetyl glutathione forms intravenous (IV) glutathione supplementation Reducing toxin exposure Supplementing with liver detoxifying compounds milk thistle, N-acetyl cysteine (NAC), superoxide dismutase (SOD), and undenatured whey protein Past controversies have argued that oral glutathione supplements were not bioactive, rendering most oral supplements useless

2016, pp