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More recently, the SELECT trial showed that semaglutide 2.4 mg reduced cardiovascular events by 20% in patients with established cardiovascular disease and overweight/obesity without diabetes

The ACHIEVE program for type 2 diabetes includes ACHIEVE-1 (NCT05971940, completed), ACHIEVE-2 (NCT06192108, completed), ACHIEVE-3 (NCT06045221, completed), ACHIEVE-4 (NCT05803421), ACHIEVE-5 (NCT06109311, completed), and ACHIEVE-J (NCT06010004, Japan-specific)

The timelines are real, the mechanism is understood, and the protocol is individualized at intake by a licensed APRN who reviews your specific history before the first dose

doi: 10.1016/j.ctrv.2009.07.002 45 KobayashiH

(Article in Japanese) Moi P, Chan K, Asunis I, et al