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A licensed healthcare provider must evaluate your heart health, kidney function, and psychiatric history before you combine these drugs

Providers often use a start low and go slow approach to help minimize side effects

When you increase doses, your system establishes a new steady state at the higher concentration over another 4-5 weeks

Additionally, improvements in blood pressure, lipid profiles, and markers of hepatic steatosis have been observed with semaglutide therapy

Should you have previously settled on a lower maintenance dose but feel like you have hit a plateau and want to increase the strength, you can do so as long as it has been at least four weeks since your last titration