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10 Additionally, GLP1 RA use has notable challenges: frequent gastrointestinal side effects, risk for nutritional deficiencies, muscle and bone loss, high costs and limited accessibility

The FDA has been tightening enforcement as shortages resolve

Importantly, both compounded and counterfeit products are often dispensed in multi-dose vials with syringes labeled in units or mg rather than mL, which has led to numerous inadvertent overdoses

It has a characteristic tarry colour and offensive smell and is often difficult to flush away

It also undergoes lower temperatures during processing and comes hydrolyzed for bioavailability & mixability