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for example, in patients with gliomas, methylation of the promoter of the DNA-repair enzyme O6-methylguanine-DNA methyltransferase (MGMT) is a problem in cancer therapy with alkylating agents [139] (Table 2)

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Conducted in 5 countries, the study compared semaglutide 2.4 mg with placebo among 304 adults without diabetes who were obese or overweight and had at least 1 weight-related comorbidity

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