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Critically, GHK-Cu delivers copper as cofactor for lysyl oxidase and lysyl hydroxylase, copper-dependent enzymes essential for collagen cross-linking and stability

Suliman M, Buckley A, Al Tikriti A, Tan T, le Roux CW, Lessan N, et al

Normal sperm motility is around 55% to 75%, which decreases 5 to 10% on average per hour

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This age-related decline is one of the most frequently cited data points in copper-peptide research literature, and its a primary reason GHK-Cu is studied within the broader context of cellular aging and peptides for longevity research rather than treated purely as a wound-healing or dermatology compound