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Further analyses revealed that both CBSA-induced MN rats and IMN patients displayed increased mRNA expression of AHR and its downstream genes CYP1A1 , CYP1A2 , and CYP1B1 , accompanied by decreased cytoplasmic AHR and increased nuclear AHR protein expression in renal tissue ( Figure 3 ) [132]

Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using stratified (by study) Cox regression models, with subgroup by treatment interaction terms added to test for heterogeneity

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Protein cages and nanostructures constructed from protein nanobuilding blocks