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Table 46 Composition of co-formulation vehicles varying in HP-B-CD content and molar substitution degree as well as in overall buffer composition 1 MS: molar substitution, corresponds to hydroxy propyls per glucose unit Preparation process Formulations were prepared as described in example 1 except that active pharmaceutical ingredients were not added

Precedent: CagriSema Success Supports Combination Approach The strongest evidence supporting a cagrilintide blend with retatrutide comes from Novo Nordisk's CagriSema program, which combines cagrilintide with semaglutide (a GLP-1 receptor agonist)

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