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Common adverse effects observed in clinical trials include nausea, vomiting, injection site reactions, increased heart rate, and hypoglycaemia risk

In parallel, some patients experience subjective cognitive decline , often described as chemo brain or chemo fog, characterized by reduced attention, memory lapses, and slowed mental processing

Genetic Considerations and Personalized Medicine The presence of variants in the MTHFR gene can increase susceptibility to various diseases , particularly when diet and lifestyle are inadequate

Statistical analysis The collected data was coded, processed, and analyzed using the SPSS (Statistical Package for Social Sciences) version 27 for Windows (IBM SPSS Inc, Chicago, IL, USA)