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In another study evaluating the potential of Pinoresinol-4- O --d-glucopyranoside (Pgu) using the lithium/pilocarpine-induced rat model, seizure induction caused an increase in the levels of malondialdehyde (MDA) a marker of oxidative lipid damageand decreased catalase activity, while also increasing the expression levels of PTGS2, all of which was reversed by Pgu pretreatment, which also mitigated neurodegeneration 47

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J Biol Chem (1986) 261:225663

The effect of vitamin E and l-carnitine against methotrexate-induced injury in rat testis

Structure, function, and regulation of human cystine/glutamate transporter in retinal pigment epithelial cells