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This can create an environment conducive to Candida overgrowth

As of time of publication, all further trials were happening in China with no phase 2 or 3 trials active anywhere else

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Potential drug interactions also warrant attention, as probiotics may alter the pharmacokinetics or efficacy of immunosuppressive therapies, thereby increasing infection risk or compromising therapeutic outcomes, posing particular concerns for patients undergoing chemotherapy, organ transplant recipients, and individuals with HIV/AIDS

Most patients notice meaningful appetite reduction within 1-2 weeks, but the strongest effects typically emerge around week 3-4 when steady-state medication levels are reached