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Epunctanone, a benzophenone metabolite from Garcinia epunctata Stapf [Clusiaceae
CMA involves the identification of KFERQ-like motifs present in the cytosolic proteins by heat shock cognate 71 kDa protein cytosolic (Hsc70c), a chaperone protein, followed by the direction to the lysosomal membrane receptor lysosomal-associated membrane protein 2A and the translocation of cargo proteins to the lysosomal lumen (5)
In 2023 the FDA placed CJC-1295 in "Category 2" of its interim 503A bulks list, meaning it identified significant safety concerns and did not permit its use in traditional pharmacy compounding
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