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The differences in the individual contributions of NADPH and NADH to the FLIM signals in the different compartments could also be due in part to the fact that in the liver, mitochondrial (free) [NAD + ]/[NADH] was found to be 7.7, roughly one hundred-fold more reduced than the hepatic cytoplasmic [NAD + ]/[NADH], which was found to be roughly 700 (Veech et al., 2019)

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