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Clinical efficacy Zepbound has been clinically shown to provide substantial weight loss, with an average of 15-18% of body weight loss over 72 weeks of treatments

Semaglutide vs Tirzepatide in T2D (SURPASS-2) SURPASS-2 (Frias et al., New England Journal of Medicine , 2021) ran tirzepatide head-to-head against semaglutide 1 mg in 1,879 adults with type 2 diabetes over 40 weeks

When combined with improved nutrition and regular activity, outcomes tend to be more sustainable

Dietary habits and lifestyle factors significantly impact symptom duration and severity

Genitourinary syndrome of menopause (GSM) is driven by low or fluctuating oestrogen and is characterised by vulvovaginal dryness, irritation, dyspareunia, recurrent infections/urinary symptoms, and tissue fragility