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[DOI: 10.1152/ajplung.00341.2013] [DOI] [PMC free article] [PubMed] [Google Scholar] 25.Vaughan AE, Brumwell AN, Xi Y, Gotts JE, Brownfield DG, Treutlein B, Tan K, Tan V, Liu FC, Looney MR, Matthay MA, Rock JR, Chapman HA
Biotechnol Mol Biol Rev
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Both enzymes use molecular oxygen to mainly oxidize the diphenols present in grape must and wine such as caftaric and cutaric acids, catechin and other flavanols, anthocyanin, and flavanone, though laccase is able to oxidize a wider range of substrates than tyrosinase [5, 7, 8]
Although the general mechanisms of APAP-induced liver injury appear to be very similar in the 2 substrains [132], the risk for experimental design is that there is a mismatch in the substrains between WT and KO mice, which can lead to misinterpretation of the data
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