successfully predicted cetuximab sensitivity in CRC PDX models by incorporating multi-omics data, providing a novel strategy for precision screening of targeted therapies [181]
These include interactions of the SNIP1 N-terminus with Smad4, a modulator of TGF- signaling 51,112 , and with RelA/p65, a transcription factor in the NF-B pathway 110 , as well as P-Thr-independent interaction of its C-terminal FHA domain with c-Myc, a protooncogene and transcriptional driver of cellular proliferation 52,53,55
They are sections of DNA, your bodys master manual, and at the latest estimate, there are around 20,000 genes in the human genome
Molecular Characteristics Molecular Type: Synthetic research peptide Structure: Linear peptide chain Stability: High when stored and handled per protocol Molecular Weight: Sequence-dependent Stability and Storage Profile Stable when stored lyophilized at 20C Sensitive to moisture and prolonged light exposure Degradation increases predictably above room temperature Reconstituted solutions remain stable for approximately 2448 hours under refrigeration Aliquot after reconstitution to minimize freezethaw cycles Solubility and Reconstitution Options Bacteriostatic water Sterile saline solutions Mildly acidic buffers Organic solvents used for analytical testing Technical Specifications product Name BPC-157 Peptide 5mg cas 137525-51-0 purity 99% (HPLC verified) unit Size 5 mg form Lyophilized powder synthesis Solid-Phase Peptide Synthesis (SPPS) analytical HPLC, Mass Spectrometry, UV Spectrophotometry Analytical Validation and Quality Control High-Performance Liquid Chromatography (HPLC) purity profiling Mass Spectrometry (MS) molecular weight confirmation UV spectrophotometric analysis Batch identity and purity verification Endotoxin and microbial contamination screening Regulatory and Compliance Information BPC-157 Peptide 5mg is supplied strictly for laboratory research and scientific investigation
Endocrinology (1999) 140(11):535663
