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I've brought this up before on this forum and got all the same kind of advice you got, and I do everything properly, and I've been doing it once or twice a week for years, so for me it's just become a fact of life that it's going to hurt

The tonicity is preferably from half to twice as high as that of physiological saline, more preferably from three-quarters to one and a half as high as that of physiological saline

This has led us to include it in many of our mobile IV options, including Limitless for Ultimate Wellness, the Revive Myers Cocktail, our Resurrect Hangover Recovery therapy, and more

in Nature Medicine demonstrated that blocking NNMT in white adipose tissue increased energy expenditure, reduced fat mass, and improved insulin sensitivity in animal models even without changes in diet or activity (Kraus et al., Nature Medicine )

It is not a replacement for prescribed mental health treatment, and severe depression should always be managed by a licensed clinician