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Lip darkening (hyperpigmentation) can occur for many reasons, some of which include: Sun exposure: The skin on our lips is sensitive and sun exposure can increase the amount of pigment (color) in the skin
If you experience these, simply lowering your daily dose or switching to a liposomal formatwhich is often easier on the stomachcan help resolve the discomfort.
UV exposure and pollution are likely to cause pigmentation problems again if you skip using it
At ambient temperature
One-quarter (n = 69) of those enrolled were affected by a mecasermin shortage over the course of the study, resulting in a dosage decrease or dose interruption
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