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doi: 10.1038/s41598-023-40011-0 46 AlemannoFHoudayerEParmaASpinaADel FornoAScatoliniAet al

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Finally, our findings are consistent with the significantly increased AMPK expression in pre-infusion CD19-CAR T cell products of patients in complete response compared to non- or partial responders as well as decreased functionality of CD19-CAR T cells upon AMPK inhibition 23

Vit-D can modulate both innate and adaptive immune responses, and vit-D deficiency is linked to increased autoimmunity as well as increased susceptibility to microbial infections

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