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The compound's ability to restore tissue homeostasis and reverse age-related functional decline in animal models provides direct evidence for the role of senescent cells in aging processes, while its applications in cancer research offer insights into senescence mechanisms in disease progression and administration resistance

We find that these interventions can partially prevent a loss of ovarian function and functional fertility caused by the anthracycline chemotherapy drug doxorubicin (Dox), and importantly, that this protection against infertility does not come at the cost of reduced efficacy of chemotherapy against cancer cell lines in vitro or tumour models in vivo

Infect Dis Ther

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