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It is a convergent architecture: a peptide that modulates NO bioavailability at the eNOS level, drives VEGF-mediated angiogenesis at the transcriptional level, protects cell-matrix adhesion through FAK-paxillin signaling, and attenuates local inflammatory cascades through apparent NF-B modulation all of this through a structurally stable, proteolysis-resistant scaffold that delivers these signals intact to target tissues

[PubMed: 3037703] 64

Originally studied for its healing properties, this peptide is now being recognized for its ability to help with muscle growth, recovery, and overall physical performance

Hippocampi from P4 Sprague Dawfey rats were cultured as previously described (Wayman, Impey et al