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Preclinical research links it to three main mechanisms: VEGFR2/eNOS angiogenic signaling, Src-caveolin-1-eNOS nitric oxide modulation, and FAK/paxillin cell-migration signaling
10.1016/j.bbamem.2015.02.011 69
Such complaints have been described in literature from 1900 onwards and may precede abnormal blood counts
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The purpose of this review is to comprehensively summarize the multidimensional biological effects of the carnitine pool beyond its traditional role in fatty acid oxidation and to summarize the systemic effects mediated by carnitine/acylcarnitine to provide new perspectives for pharmacological research and treatment innovation and new strategies for the prevention and treatment of a variety of diseases
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