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What this data doesn't tell us: whether NNMT suppression sustained beyond 12 weeks alters NAD+ metabolism in ways that affect mitochondrial function, whether methylation pathway compensation occurs over longer timescales, or whether adipose tissue remodeling continues linearly or plateaus

FDA-watchers say the most likely outcome may be a temporary policy reassuring pharmacies that they won't be targeted for compounding the peptides under review

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It has not yet received FDA approval, so it is classified as a research compound