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Skin barrier dysfunction and systemic sensitization to allergens through the skin

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Curr Opin Investig Drugs 10:463473 Li Q, Han Y, Dy ABC, Hagerman RJ (2017) The gut microbiota and autism spectrum disorders

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The GI side effect data is equally important

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A more recent study demonstrated that the delivery of instability-prone Mecp2 ( iMecp2 ) transgene cassette using an adeno-associated virus (AAV) vector in symptomatic Mecp2 mutant mice significantly improved locomotor activity, lifespan and normalized gene expression [44]

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