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However, advancement through Phase 3 trials and approval requires substantial investment

2.2.4 Roles of defensins in abiotic stresses 2.2.4.1 Defensin-mediated mechanisms for heavy metal tolerance A primary mechanism for heavy metal tolerance is the chelation of metal ions by the cysteine-rich domains of defensins, followed by the efflux of the metal-defensin complex from the cytoplasm to less sensitive extracellular compartments like cell walls or the apoplast, or into vascular tissues for transport (Luo et al., 2018

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Its applications include injury, pain, and digestive disorders