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3), with digital treatment being the most prominent application (Table 1)
Given that M-cells have well-accepted BT capability and overlie intestinal lymphoid aggregates, M-cell mediated BT is one plausible mechanistic explanation [16, 17]
Additionally, integrating metagenomics with metabolomics to identify key functional bacteria involved in metabolic processes and their metabolites will help elucidate the dialogue mechanism underlying "TCM components-GM-host" interactions
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On the other hand, mitochondrial dysfunction signs include acylcarnitine enhancement, malfunction in -oxidation of fats, and the presence of mitochondrial DNA in blood
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