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Richard Choi (@rkchoi) for thoughtful comments on this chapter

SURPASS-3 MRI, a sub-study of the phase-3 SURPASS-3 trial assessed tirzepatide administered once per week versus insulin degludec on liver fat content (LFC)

But newer research revealed that GIP receptor activation in the brain actually reduces appetite, and when combined with GLP-1 receptor activation, the metabolic benefits multiply

Hormones, metabolism, sleep quality, stress, insulin resistance, thyroid function, medications, and nutrient deficiencies can all play a role in how the body gains, stores, and loses weight

"Immune checkpoint inhibitors have revolutionized our approach to the treatment of cancer