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About OASIS 4 OASIS 4 was a 64-week phase 3 randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of once-daily oral semaglutide 25 mg versus placebo in 307 adults with obesity (BMI 30 kg/m 2 ) or overweight (BMI 27 kg/m 2 ) with one or more weight-related comorbidities

Beyond this period, the medications potency is not guaranteed

Acknowledgments We acknowledge the use of OpenAIs ChatGPT (version: GPT-4, model: gpt-4-turbo) for language editing and refinement of the manuscript

Potential side effects may include: Water retention Joint pain Numbness or tingling Insulin resistance Headaches Hormonal imbalances Injection site reactions More serious concerns include: Long-term cancer risk (due to IGF-1 stimulation) Endocrine disruption Unknown contamination in unregulated products Additionally, many peptides are banned by sports organizations, such as the World Anti-Doping Agency

Peptide therapy generally isnt covered by insurance as it involves compounded medications