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This GLP-1 receptor agonist is licensed by the MHRA for weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with weight-related comorbidities, as an adjunct to a reduced-calorie diet and increased physical activity

This is not a matter of the evidence being weak or preliminary

They also make your body more resistant to insulin and can increase inflammation, both of which get in the way of how well GLP-1 works

Specific situations requiring medical advice include: consistently elevated blood pressure readings above 140/90 mmHg (or above the individual target set by their healthcare team), symptoms suggesting low blood pressure such as recurrent dizziness or fainting, or any new cardiovascular symptoms including chest pain, palpitations, or unusual shortness of breath

You started Zepbound, Wegovy, or similar elsewhere and stalled