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This table summarizes recent drugs or intervention strategies targeting amino acid metabolism-related pathways, including regulatory approaches directed at metabolic axes such as arginine (Arg), tryptophan (Trp), glutamine (Gln), and serine (Ser), as well as their potential roles in the regulation of macrophage polarization and inflammatory responses
Schreiber R, et al
By elucidating how these systemic metabolic disturbances converge to induce selective ferroptotic damage in vulnerable hippocampal and cortical neurons, the work establishes a direct mechanistic link between general diabetic complications and cognitive decline, thereby bridging the related research fields
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