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Second, cancer cells require more iron to grow and have higher ROS levels compared to normal cells, which makes cancer cells more susceptible to ferroptosis (Zhang et al., 2022d)

11 As such, PRP constituents include growth factors for anabolism, inflammatory mediators, and fibrinogen

The function of GPX3 as an extracellular antioxidant enzyme in the cytosol and mitochondria can affect the fatty acid metabolism of tumor stem cells, and the levels of GSH and unsaturated fatty acids in the TME (120)

Methionine:An essential amino acid that helps break down fats, prevents fat accumulation in the liver and arteries, and aids in detoxification processes