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Infection: Poor hygiene can cause local infections or, rarely, systemic ones

Preclinical cartilage evidence Kwon and Park 2015 in Annals of Clinical and Laboratory Science reported that intra-articular AOD-9604 plus hyaluronic acid in a rabbit knee osteoarthritis model improved cartilage histology and reduced lameness compared with hyaluronic acid alone

It is used to increase collagen and elastin in the skin to make it tight and smooth