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Clin Endocrinol (Oxf) (2013) 79:58490

Histamine is a signaling molecule used throughout the immune system, gastrointestinal tract and nervous system

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doi: 10.1016/j.plaphy.2024.108451 128 WebberH.EwertF.OlesenJ

Affected individuals may show other non-motor symptoms, with some being GI-oriented and emerging years before the classical motor features (Cersosimo et al., 2013)