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In line with the effects of selenium metabolism and selenoproteins in chondrogenic progenitor cells observed in vitro, deficient uptake of selenium severely affected chondrogenic differentiation of mesenchymal lineage cells and thus endochondral ossification in mice 64
However, potential side effects can include: Nausea or dizziness (rare) Headaches Injection site irritation Overstimulation or fatigue if overdosed There are no long-term human trials, so effects on hormones, organs, or chronic use remain unknown
Abstract Clinical and pre-clinical evidence demonstrates that adolescent -9-tetrahydrocannabinol (THC) exposure, the primary psychoactive component of cannabis, increases the risk of developing neuropsychiatric symptoms in later life
10.1016/j.phrs.2021.105466 13
modulation of matrix metalloproteinase (MMP) activity and their tissue inhibitors (TIMPs)
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