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We may speculate that this study provides an insight into how zinc sufficiency is important for BHMT functionality, since BHMT is a zinc dependent enzyme that catalyses the transmethylation of homocysteine to methionine in the presence of the methyl group donor betaine

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There has been extensive preclinical in vitro and in vivo research showing the relationship between metals such as copper, zinc, and iron and the onset and progression of neurodegenerative conditions such as Alzheimers disease

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