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The recommended weekly dose in milligrams (mg) per kilogram (kg) of body weight for pediatric patients is: Pediatric GH Deficiency: 0.18 mg/kg/week to 0.3 mg/kg/week (0.026 mg/kg/day to 0.043 mg/kg/day) Turner syndrome: Up to 0.375 mg/kg/week (up to 0.054 mg/kg/day) Idiopathic short stature: Up to 0.37 mg/kg/week (up to 0.053 mg/kg/day) SHOX Deficiency: 0.35 mg/kg/week (0.05 mg/kg/day) Small for Gestational Age (SGA): Up to 0.47 mg/kg/week (up to 0.067 mg/kg/day) In very short pediatric patients, HSDS less than -3, and older pubertal pediatric patients consider initiating treatment with a larger dose of ZOMACTON 5mg IU injection (up to 0.067 mg/kg/day)

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Hao, J., Cheng, L., Chen, D., Yue, Y., Qiu, C., Wu, R., Fan, L., Bao, M., Gong, L., Guo, Y., An, L., Tian, J., and Xi, G.: L-Carnitine and vitamin C improve the quality of sheep oocytes after in vitro maturation and subsequent pregnancy outcome, Free Radical Bio

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This means adults who are obese or overweightwith at least one weight-related health condition such as high blood pressure, high cholesterol, or type 2 diabetesmay benefit from this new treatment