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PNAS 2018] SUMMARY OF PAIN MEDICATION USE There is ample evidence that long-term narcotic use is detrimental to sperm quality, though short-term use of these medications for an acute event (such as recovery after a surgical procedure) likely has no significant impact

ChaC2 may be implicated in numerous vital physiological functions, including DNA replication and repair, cell cycle regulation, RNA and damaged DNA binding, oocyte meiosis and maturation (50)

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Thus, reproductive senescence is a growing public health problem

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