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This can lead to disturbed calcium homeostasis and cause misfolded proteins with impaired autophagy, distorted mitochondrial dynamics, and cell death (Sunanda et al., 2021)
To demonstrate the superior efficacy of the MNs/GLP-1RAs@NPs-WYRGRL in the treatment of RA, rats were divided into NC group, RA group, RA + NPs group, RA + GLP-1RAs@NPs group, RA + GLP-1RAs@NPs-WYRGRL group, RA + MNs group and RA + MNs/GLP-1RAs@NPs-WYRGRL group, with 46 rats in each group