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The expression of HGF is decreased in HCC, but is increased in peritumoral liver tissue (Garcia-Vilas and Medina, 2018)

Improved gut integrity may enhance signaling from hormones such as GLP-1 and PYY, both of which influence satiety and metabolic control

Tirzepatide Tirzepatide, a novel dual agonist of GIP and GLP-1 receptors, has demonstrated exceptional efficacy in improving glycemic control and promoting weight loss in individuals with Type 2 diabetes mellitus (T2DM) and obesity (43)

Although L-carnitine deficiency is an infrequent problem in a healthy, well-nourished population consuming adequate protein, many individuals within the population appear to be somewhere along a continuum, characterized by mild deficiency at one extreme, and tissue pathology at the other

While the exact mechanisms leading to NASH are still unclear, the prevalence of obese patients diagnosed with NASH strongly suggests lack of blood sugar control, insulin resistance, and blood lipid problems may play a significant role (2)