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In contrast, pathways involved in metabolism, such as alanine, aspartate, and glutamate metabolism, biosynthesis of secondary metabolites, and C5-branched dibasic acid metabolism, displayed a balance of upregulated and downregulated genes

& Neels, H

The case of NAC encapsulates the core challenges of MIRI therapy: while its mechanism of enhancing endogenous defenses is conceptually superior to direct scavenging (as argued in Section 2.3), its clinical potential is ultimately nullified by the formidable practical hurdles of delivery and timing required to counteract the rapid and localized oxidative burst (Section 2.1)

Most patients notice increased energy within 2-4 weeks

Advances in control technologies and mechanisms to treat peel browning in postharvest fruit