Harvard University Press, Cambridge, Massachusetts
Excessive oxidative stress may induce oxidative modifications, including peroxidation of mitochondrial lipids, oxidative damage of mitochondrial proteins including OXPHOS components, cristae remodeling, mutations and severe damage in mitochondrial DNA (mtDNA) [5, 6, 22, 39, 40, 42, 43]
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These participant covariates included age, sex, body mass index calculated from measured height and weighed height for age and sex adjustment, education level, sleep quality evaluated through questionnaire using the Pittsburgh Sleep Quality Index 19 , eating habits assessed via a valid food frequency questionnaire, and environmental exposure history such as secondhand smoke exposure and occupational respiratory hazard
