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Pharmacokinetics of 1 and 2 in vivo: intraperitoneal administration Chemicals and reagents HPLC-grade water was prepared by an in-house PURELAB Option filtration system (Elga lab water solution, UK)

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Notably, a substantial proportion of retatrutide recipients (64-100%) were able to achieve a weight loss of 5% or more, a clinically significant threshold, compared to just 27% in the placebo group