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Theres evidence that polyunsaturated fatty acids like linoleic acid may act directly and indirectly on 5-alpha reductase by 1) reducing inflammation, and 2) altering lipid bilayers in cell membranes to decrease 5-alpha reductase formation

If you notice these side effects, physicians often recommend that you wait a few days

Supporting Documentation: Attach all relevant medical records: clinic notes, lab results (A1C, lipid panel), imaging, specialist consultations

A balance is needed because, at high doses of 500-600 mg, caffeine can increase heart rate and shivering[9 Trusted Source 2015 - Current neuropharmacology Caffeine: Cognitive and Physical Performance Enhancer or Psychoactive Drug

Data from two independent experiments with two technical replicates were analysed for each concentration