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This creates a planning problem most researchers don't anticipate until they're staring at leftover solution approaching its expiration

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One study in patients with T2D demonstrated that intravenously administered GLP-1 significantly reduced fasting blood glucose (FBG) and, in a glucose-dependent manner, both enhanced insulin secretion and suppressed glucagon secretion ( Figure 19 - 2 )

The development of oral GLP-1 formulations, like Novo Nordisk's recently FDA-approved Wegovy pill in December 2025 , offers a needle-free alternative that can significantly improve patient compliance and expand access to demographics hesitant about injections