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aeruginosa T3SS is induced by several conditions including low Ca 2+ and host cell contact through ExsA [[35], [36], [37]], the redox control of T3SS via Vfr could be another layer of modulation where oxidizing condition could dampen T3SS induction

doi:10.1038/nrgastro.2009.125

This is consistent with a previous report that the core apoptotic pathway genes, including CED-9/BCL-1, CED-4/APAF-1 and cell-killing caspase ced-3 , are not required for axonal fusion 16

10.1038/s41598-018-25603-5 Sci

As connective tissue is ubiquitously distributed throughout the body, manifestations of the different types of EDS are present, to varying degrees, in virtually every organ system