glp 1 and dopamine Endogenous Glucagon-like Peptide-1 Suppresses High-Fat Food Intake by Reducing Synaptic Drive onto Mesolimbic Neurons GLP-1 Medications: A Game Changer

Therap Adv Gastroenterol 2009;2:157-163

Based on available data, here is a general comparison of expected before and after results

The most reliable data comes from a 2020 systematic review and meta-analysis of 37 randomized controlled trials (about 2,300 participants)

In the intestines, butyrate plays a regulatory role on the transepithelial fluid transport, ameliorates mucosal inflammation and oxidative status, reinforces the epithelial defense barrier, and modulates visceral sensitivity and intestinal motility (Canani et al., 2011)

As such, it acts as a cellular signal for oxidative stress and is involved in the regulation of cellular states such as proliferation or apoptosis