The findings indicated that AST/Bex treatment restrained transcription and activity of the amyloidogenic enzyme BACE1, consequently decreasing A oligomers as well as 80-kDa intracellular APP/A species
KEGG and GO functional enrichment analysis To further examine the molecular function of the identified DEGs, KEGG pathway analysis indicated that the most prevalent pathways influenced by dietary WE across multiple tissues in the ZDF rats were: glutathione metabolism
The transcription factor NUPR1 prevents ferroptosis by reducing the accumulation of labile iron and oxidative damage [32]
Furthermore, the endometrium exhibits accelerated aging at a molecular level compared to other tissues, as measured by epigenetic clocks [19]
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