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Similarly, drugs like atorvastatin have been repurposed to delay ARHL progression by activating pathways such as HSF1/Sirt1, which bolster antioxidant defenses and maintain mitochondrial structure (Choo et al., 2022)

Since the immune system is also critical for identifying and eliminating malignant cells, immunosuppression from DMTs may predictably increase the risk of cancer development in MS patients