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Among adults without type 2 diabetes, a direct comparison between tirzepatide and semaglutide showed that tirzepatide was associated with higher hazards of anxiety disorders and insomnia than semaglutide, while no consistent differences were observed for most neurological outcomes after statistical adjustment
The mean duration of type 2 diabetes was 4.2 years, and the mean BMI was 33 kg/m2
ASCVD, atherosclerotic cardiovascular disease
doi: 10.1123/ijsnem.2019-0065, 9
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